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Tangential Flow Filtration (TFF) involves the recirculation of the retentate across the surface of the membrane. This gentle cross flow feed acts to minimize membrane fouling, maintain a high filtration rate and provide higher product recovery. Tangential Flow Filtration is used in both microfiltration and ultrafiltration applications. Spectrum's Hollow Fiber Tangential Flow Filter modules are particularly useful in Tangential Flow Filtration because processes can easily be scaled-up from small volume R&D applications to full-scale production. The same filtration conditions used to optimize R&D or lab scale filtration can be used in full-scale production when the length of the filtration flow path is maintained while filter's surface area is increased by adding more fibers to process large volumes.
Tangential Flow Filtration Systems are automated systems used with Hollow Fiber Filters. Spectrum's TFF systems consist of pumps with integrated digital pressure monitors and data collection software to ensure efficient and reproducible filtration.